Search results for "BRAF V600 Mutation"

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The association between dermoscopic features and BRAF mutational status in cutaneous melanoma: Significance of the blue-white veil.

2018

Background: The genetic basis of melanoma affects its clinicopathologic characteristics and increasingly influences its management. B-Raf proto-oncogene, serine/threonine kinase gene (BRAF)-mutated melanoma may present with specific dermoscopic features. Objectives: To identify the dermoscopic features associated with BRAF mutation in cutaneous melanoma and to evaluate a model capable of predicting BRAF mutations on the basis of dermoscopic and clinicopathologic features that are easily accessible in normal clinical practice. Methods: A prospective, cross-sectional, observational, and descriptive study was performed. A total of 93 cutaneous melanomas with dermoscopic images from 93 patients…

OncologyMaleSkin NeoplasmsDNA Mutational Analysisblue-white veilProto-Oncogene Mas030207 dermatology & venereal diseases0302 clinical medicineBRAF V600 MutationOdds RatioMutational statusgeneticsProspective StudiesMelanomaSanger sequencingMelanomaMiddle AgedPrognosisClinical PracticedermatologyGene Expression Regulation Neoplastic030220 oncology & carcinogenesisoncologysymbolsFemaleAdultProto-Oncogene Proteins B-rafmedicine.medical_specialtyDermoscopyDermatologyRisk AssessmentBRAF03 medical and health sciencessymbols.namesakePredictive Value of TestsInternal medicinemedicinemelanomaConfidence IntervalsHumansneoplasmsAgedbusiness.industryOdds ratiostreaksmedicine.diseaseConfidence intervalulcerationCross-Sectional StudiesCutaneous melanomapathologydermoscopybusinessexophytic papillary structuresJournal of the American Academy of Dermatology
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